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Medications

Loxapine inhalation powder

What is this medicine?

LOXAPINE (LOX a peen) inhaler is used to treat certain symptoms of schizophrenia and bipolar disorder. Bipolar disorder is also known as manic-depression.

How should I use this medicine?

This medicine is inhaled by mouth. It will only be given to you by a health care professional while you are in a hospital or clinic setting. Your healthcare professional will show you how to take this medicine right before you use it. Follow the instructions for use carefully.

A special MedGuide will be given to you before each treatment. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • changes in blood pressure or heart rate

  • changes in vision

  • chest tightness

  • confusion

  • feeling faint or lightheaded, falls

  • high fever

  • seizures

  • stiff muscles

  • sweating

  • trouble passing urine or change in the amount of urine

  • trouble swallowing

  • unusual bleeding or bruising

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • changes in taste (bad, bitter, or metallic taste)

  • constipation

  • drowsiness

  • dry mouth

  • sore throat

What may interact with this medicine?

  • alcohol

  • antihistamines for allergy, cough and cold

  • atropine

  • certain medicines for bladder problems like oxybutynin, tolterodine

  • certain medicines for blood pressure, heart disease, irregular heart beat

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl

  • certain medicines for sleep

  • certain medicines for stomach problems like dicyclomine, hyoscyamine

  • certain medicines for travel sickness like scopolamine

  • ipratropium

  • medicines that relax muscles

  • medicines used for anesthesia

  • narcotic medicines (opiates) for pain

What if I miss a dose?

This does not apply; this medicine is not for regular use.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorders

  • dehydration

  • dementia

  • glaucoma

  • heart disease

  • history of a drug or alcohol abuse problem

  • history of stroke

  • liver disease

  • low blood pressure

  • lung or breathing disease, like asthma or COPD, or currently taking medicines to treat breathing problems

  • Parkinson's disease

  • prostate disease

  • seizures

  • an unusual or allergic reaction to loxapine, amoxapine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Your condition will be monitored carefully while you are receiving this medicine.

This medicine may cause breathing problems. Your healthcare provider will check you for breathing problems before and after you take this medicine. You will be observed closely for about 1 hour after you take this medicine. Tell your healthcare provider right away if you have wheezing, coughing, chest tightness, or shortness of breath at any time after taking this medicine. Breathing problems that occur after taking this medicine may require additional treatments.

You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine and make you more dizzy. Avoid alcoholic drinks.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2017 Elsevier