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Medications

Drotrecogin Alfa Solution for injection

What is this medicine?

DROTRECOGIN ALFA (droe tre KOE gin AL fa) is used to treat life-threatening sepsis.

NOTE: Drotecogin alfa has been withdrawn from the market and is no longer available.

How should I use this medicine?

This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose

What may interact with this medicine?

  • aspirin and aspirin-like medicines

  • cilostazol

  • clopidogrel

  • dipyridamole

  • medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, heparin

  • pentoxifylline

  • ticlopidine

What if I miss a dose?

This does not apply.

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • bleeding disorders

  • brain or spine surgery or injury

  • history of any bleeding event

  • low platelet count in the blood

  • liver disease

  • stroke

  • take medicines that treat or prevent blood clots

  • an unusual or allergic reaction to drotrecogin alfa, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2018 Elsevier